Key Aspects
Jardiance is a sodium-glucose-cotransporter-2 (SGLT-2) inhibitor that is used in addition to exercise and diet to reduce blood glucose (sugar) in adults with diabetics of type 2. It lowers blood sugar by blocking kidney proteins to boost the excretion of glucose through the urine.
Jardiance decreases the chance of a heart-related death (like a stroke or heart attack) for adults with heart disease. It also reduces the possibility of hospitalization or death due to failing heart (when it is weak in the heart, and can’t deliver enough blood to rest in your body) in patients suffering from heart failure.
Over time, high blood sugar levels may cause plaque to build inside your blood vessels, increasing your risk for heart disease.
How does Jardiance work?
Jardiance (empagliflozin) is classified as an SGLT-2 (sodium-glucose cotransporter-2) inhibitor. The SGLT-2 proteins reside inside the kidney tubules of kidneys. They play a role in returning glucose into the blood. Jardiance inhibits the function that SGLT-2 protein performs. As a result, more glucose is excreted in the urine.
SGLT-2 inhibitors have been shown to be effective in lowering hemoglobin A1C levels which can aid in weight loss as well as decreasing blood pressure.
Jardiance is a good addition to other medicines used to treat type 2 diabetes, such as metformin, sulfonylureas, pioglitazone and insulin as as other heart medications like beta blockers, statins ACE inhibitors, and diuretics.
In their entirety, SGLT-2 inhibitors have an extremely low risk of having Hypoglycemia (low level of blood sugar). However, your physician may need to lower your dose of Jardiance if you take it with other drugs which can also result in low blood sugarlevels, such as insulin or Sulfonylureas.
Other FDA approved drugs in the SGLT-2 inhibitors class include:
canagliflozin (Invokana)
dapagliflozin (Farxiga)
ertugliflozin (Steglatro)
These medications are sold as single ingredient products , or when combined with other medications for diabetes.
What can Jardiance assist me with my diabetes type 2?
When you suffer from type 2 diabetes, your body does not make enough insulin. The insulin that you make does not work as well, and you may make excessive amounts of glucose (sugar). In this situation, sugar builds up in your bloodstream and could result in serious health problems related to kidneys, the heart, nerves, blood vessels and eyes. Fitness, diet and use of special medications will help lower your blood sugar level and help reduce the risk from type 2 diabetes.
Many people who are first discovered to have type 2 diabetes are on an oral medication known as metformin. It’s in the class of drugs known as biguanides. It improves the ability of cells to utilize glucose (blood sugar) by enhancing the way that your insulin works and decreases the absorption of glucose from your liver.
Some patients are unable to attain their blood sugar goals using metformin by itself and will require an additional dose of medication. Get in touch for Jardiance coupon.
Jardiance is a supplement to metformin or other medicines to help you reach your A1C goal. A1C is a straightforward blood test that reveals the average level of sugar (glucose) in your blood over the past 2 to 3 months, letting you know how your blood sugar levels are being managed over time.
Who shouldn’t use Jardiance?
Jardiance should never be used in patients suffering from type 1 diabetes or diabetic ketoacidosis (increased ketones found in urine or in the blood). In patients suffering from type 1 diabetes may increase the risk of diabetes ketoacidosis.
It is not recommended to use Jardiance if you’ve ever had an extreme allergic reaction to Jardiance of any of its components.
It is also advised not to use this drug if you have an extremely severe kidney (renal) disease, end-stage renal disease, or you are on dialysis. Your doctor will test your kidney function before you start treatment with Jardiance. Jardiance could not work for you if you have serious kidney issues.
How do I take Jardiance?
Take Jardiance daily, exactly as your physician tells you. It is available as a 20 mg and 25 mg tablets that you take.
The dosage recommended for Jardiance of 10 mg once every day in the morning and taken without or with food. If you’re able to tolerate Jardiance dosage, it can get increased up to 25 mg if you need it.
Your doctor will examine the function of your kidneys with a blood test before you begin treatment. If you have a certain level of kidney disease, you might not be able to take advantage of Jardiance.
Don’t take Jardiance If you have an allergy to one of the ingredients.
Jardiance is not suitable for use by anyone less than 18 years of age.
Significant side effects associated with Jardiance
Jardiance can generally be tolerated. However, like any drug, there are some serious side effects. You must discuss and review the effects with your physician.
The most serious side effects associated with Jardiance may include:
Ketoacidosis (increased ketones in your urine or in your blood)
Sudden kidney injury
Urinary tract infections
Dehydration (the loss of body’s water and salt)
Blood sugar levels are low (hypoglycemia)
Necrotizing fasciitis (a extremely rare, but severe tissue infection that occurs under the skin and can develop around the anus and the genitals)
Allergy reactions
The increase in cholesterol
The most common adverse symptoms (5 percent or more) that could be experienced with Jardiance are:
Urinary tract infections
Infections caused by yeast
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